SLC8A2

Protein name: NCX2 Aliases: N/D Substrates: Na+, Ca2+ Transport type: Exchanger / Na+, Ca2+ Tissue and cellular expression: abundant in neurons in all parts of the brain, but not present at significant levels elsewhere Subcellular expression: N/D Disease: N/D Locus: 19q13.3 Sequence ID: NP_055878.1, NM_015063.2 Gene ID: 6543 Splice variants: no splice variants found

NAC2_HUMAN (UniProt)

Gene names: SLC8A2, KIAA1087, NCX2
Protein names and data: NAC2_HUMAN, Full=Sodium/calcium exchanger 2, Full=Na(+)/Ca(2+)-exchange protein 2;Flags: Precursor; Length: 921 a.a., Mass: 100368 Da,
fasta formatted sequence

Function: Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores (By similarity)
Cellular location: Membrane; Multi-pass membrane protein

Database cross-references

UniProt: Q9UPR5
NextBio: 25461
OMIM: 601901
Ensembl: ENST00000236877
GeneCard: GC19M047428
PharmGenUCSF: SLC8A2
Guide to Pharmacology: SLC8A2 (946)
SLC8 family of sodium/calcium exchangers (946)

HGNC: HGNC:11069

Genetic variants

See also Ensembl:ENST00000236877