Protein name: N/D Aliases: DAT, DAT1 Substrates: dopamine Transport type: N/D Tissue and cellular expression: brain (dopaminergic neurons), gut Subcellular expression: N/D Disease: Parkinson disease, Tourette syndrome, ADHD, addiction, major affective disoorders Locus: 5p15.3 Sequence ID: NP_001035.1, NM_001044.4 Gene ID: 6531 Splice variants: N/D

SC6A3_HUMAN (UniProt)

Gene names: SLC6A3, DAT1
Protein names and data: SC6A3_HUMAN, Full=Sodium-dependent dopamine transporter;Short=DA transporter;Short=DAT, Full=Solute carrier family 6 member 3; Length: 620 a.a., Mass: 68495 Da,
fasta formatted sequence

Function: Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals
Cellular location: Membrane; Multi-pass membrane protein

Database cross-references

UniProt: Q01959
NextBio: 25411
OMIM: 126455 613135
Ensembl: ENST00000453492
GeneCard: GC05M001392
TCDB: 2.A.22.1.3
PharmGenUCSF: SLC6A3
Guide to Pharmacology: SLC6A3 (927)
Monoamine transporter subfamily (927)

HGNC: HGNC:11049

Genetic variants

See also Ensembl:ENST00000453492