Protein name: N/D Aliases: B0AT3, XT2 Substrates: neutral amino acids Transport type: N/D Tissue and cellular expression: kidney (proximal tubule) Subcellular expression: N/D Disease: hyperglycinuria?, hypertension? Locus: 5p15.33 Sequence ID: NP_872438.2, NM_182632.2 Gene ID: 348932 Splice variants: N/D

S6A18_HUMAN (UniProt)

Gene names: SLC6A18, XTRP2
Protein names and data: S6A18_HUMAN, Full=Sodium-dependent neutral amino acid transporter B(0)AT3, Full=Sodium- and chloride-dependent transporter XTRP2;Full=Solute carrier family 6 member 18;Full=System B(0) neutral amino acid transporter AT3; Length: 628 a.a., Mass: 70897 Da,
fasta formatted sequence

Function: Functions as a sodium and chloride-dependent neutral amino acid transporter (By similarity)
Cellular location: Membrane; Multi-pass membrane protein (Probable)
Tissue specificity: Abundantly expressed in kidney, but not in intestine

Database cross-references

UniProt: Q96N87
NextBio: 99455
OMIM: 610300
Ensembl: ENST00000324642
GeneCard: GC05P001225
TCDB: 2.A.22.6.4
PharmGenUCSF: SLC6A18
Guide to Pharmacology: SLC6A18 (941)
Neutral amino acid transporter subfamily (941)

HGNC: HGNC:26441

Genetic variants

Genetic variation in SLC6A18 is not a significant predictor for elevated systolic or diastolic blood pressure and is not associated with hypertension in the Japanese population. See also Ensembl:ENST00000324642