SLC41A1

Protein name: MgtE Aliases: N/D Substrates: Mg2+ (Sr2+, Zn2+, Cu2+, Fe2+, Co2+, Ba2+, Cd2+) Transport type: Cotransporterh Tissue and cellular expression: kidney, heart, testis, skeletal muscle, prostate, adrenal gland, thyroid Subcellular expression: N/D Disease: mutations in PARK16 locus Locus: 1q32.1 Sequence ID: NP_776253.3, NM_173854.4 Gene ID: 254428 Splice variants: N/D

S41A1_HUMAN (UniProt)

Gene names: SLC41A1
Protein names and data: S41A1_HUMAN, Full=Solute carrier family 41 member 1; Length: 513 a.a., Mass: 54901 Da,
fasta formatted sequence

Function: Acts as a magnesium transporter that is responsive to magnesium balance
Cellular location: Cell membrane; Multi-pass membrane protein
Tissue specificity: Highest expression levels in heart and testis, slightly less in skeletal muscles, prostate, adrenal gland and thyroid, and weakest in the hematopoietic tissues bones marrow, lymph node, thymus and spleen

Database cross-references

UniProt: Q8IVJ1
NextBio: 92351
OMIM: 610801
Ensembl: ENST00000367137
GeneCard: GC01M205789
TCDB: 9.A.19.4.1
PharmGenUCSF: SLC41A1
Guide to Pharmacology: SLC41A1 (1195)
SLC41 family of divalent cation transporters (1195)

HGNC: HGNC:19429

Genetic variants

See also Ensembl:ENST00000367137