SLC39A6
Protein name: ZIP6, LIV-1 Aliases: N/D Substrates: Zn Transport type: N/D Tissue and cellular expression: widespread Subcellular expression: plasma membrane Disease: breast, pancreatic, cervicale, prostate cancer, neuroblastoma Locus: 18q12.1 Sequence ID: NP_001092876.1, NM_001099406.1 NP_036451.3, NM_012319.3 Gene ID: 25800 Splice variants: N/DS39A6_HUMAN (UniProt)
Gene names: SLC39A6, LIV1, ZIP6Protein names and data: S39A6_HUMAN, Full=Zinc transporter ZIP6, Full=Estrogen-regulated protein LIV-1;Full=Solute carrier family 39 member 6;Full=Zrt- and Irt-like protein 6;Short=ZIP-6;Flags: Precursor; Length: 755 a.a., Mass: 85047 Da,
fasta formatted sequence
Function: May act as a zinc-influx transporter
Cellular location: Cell membrane; Multi-pass membrane protein
Tissue specificity: Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma
Database cross-references
UniProt: Q13433NextBio: 46997
OMIM: 608731
Ensembl: ENST00000440549
GeneCard: GC18M036108
PharmGenUCSF: SLC39A6
Guide to Pharmacology: SLC39A6 (1185)
SLC39 family of metal ion transporters (1185)
HGNC: HGNC:18607