Protein name: ZIP1, ZIRTL Aliases: N/D Substrates: Zn Transport type: N/D Tissue and cellular expression: widespread Subcellular expression: plasma membrane, intracellular vesicles Disease: prostate cancer, neurodegeneration Locus: 1q21 Sequence ID: NP_055252.2, NM_014437.3 Gene ID: 27173 Splice variants: N/D

S39A1_HUMAN (UniProt)

Gene names: SLC39A1, IRT1, ZIP1, ZIRTL, CGI-08, CGI-71
Protein names and data: S39A1_HUMAN, Full=Zinc transporter ZIP1, Full=Solute carrier family 39 member 1;Full=Zinc-iron-regulated transporter-like;Full=Zrt- and Irt-like protein 1;Short=ZIP-1;Short=hZIP1; Length: 324 a.a., Mass: 34250 Da,
fasta formatted sequence

Function: Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells
Cellular location: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Shows a vesicular localization corresponding partially to the endoplasmic reticulum in several epithelial cell lines
Tissue specificity: Ubiquitous. Expressed in most adult and fetal tissues including the epidermis

Database cross-references

UniProt: Q9NY26
NextBio: 49976
OMIM: 604740
Ensembl: ENST00000368623
GeneCard: GC01M153931
TCDB: 2.A.5.3.2
PharmGenUCSF: SLC39A1
Guide to Pharmacology: SLC39A1 (1180)
SLC39 family of metal ion transporters (1180)

HGNC: HGNC:12876

Genetic variants

See also Ensembl:ENST00000368623