SLC36A1

Protein name: PAT1 Aliases: LYAAT1 Substrates: GABA, P, G, beta-alanine Transport type: Cotransporter / H+ Tissue and cellular expression: brain, intestine, colon, kidney, lung, liver, spleen Subcellular expression: N/D Disease: N/D Locus: 5q33.1 Sequence ID: NP_510968.2, NM_078483.2 Gene ID: 206358 Splice variants: N/D

S36A1_HUMAN (UniProt)

Gene names: SLC36A1, PAT1
Protein names and data: S36A1_HUMAN, Full=Proton-coupled amino acid transporter 1;Short=Proton/amino acid transporter 1;Short=hPAT1, Full=Solute carrier family 36 member 1; Length: 476 a.a., Mass: 53076 Da,
fasta formatted sequence
Function: Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognize their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity)
Cellular location: Cell membrane; Multi-pass membrane protein (By similarity). Lysosome membrane; Multi-pass membrane protein

Database cross-references

UniProt: Q7Z2H8
NextBio: 90533
OMIM: 606561
Ensembl: ENST00000520701
GeneCard: GC05P151413
PharmGenUCSF: SLC36A1
Guide to Pharmacology: SLC36A1 (1161)
SLC36 family of proton-coupled amino acid transporters (1161)
HGNC: HGNC:18761

Genetic variants

See also Ensembl:ENST00000520701