Protein name: PAPST2 Aliases: CGI-19, C6orf196 Substrates: PAPS Transport type: N/D Tissue and cellular expression: ubiquitous Subcellular expression: Golgi Disease: N/D Locus: 6p24.3 Sequence ID: NP_001136012.1, NM_001142540.1 NP_001136013.1, NM_001142541.1 NP_057032.2, NM_015948.3 Gene ID: 51000 Splice variants: N/D

S35B3_HUMAN (UniProt)

Gene names: SLC35B3, C6orf196, PAPST2, CGI-19
Protein names and data: S35B3_HUMAN, Full=Adenosine 3'-phospho 5'-phosphosulfate transporter 2, Full=3'-phosphoadenosine 5'-phosphosulfate transporter;Full=PAPS transporter 2;Full=Solute carrier family 35 member B3; Length: 401 a.a., Mass: 44593 Da,
fasta formatted sequence

Function: Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon
Cellular location: Golgi apparatus membrane; Multi-pass membrane protein
Tissue specificity: Preferentially and highly expressed in colon

Database cross-references

UniProt: Q9H1N7
NextBio: 53452
OMIM: 610845
Ensembl: ENST00000379660
GeneCard: GC06M008413
TCDB: 2.A.7.11.5
PharmGenUCSF: SLC35B3
Guide to Pharmacology: SLC35B3 (1145)
SLC35 family of nucleotide sugar transporters (1145)

HGNC: HGNC:21601

Genetic variants

See also Ensembl:ENST00000379660