SLC35B2

Protein name: PAPST1 Aliases: UGTrel4, SLL Substrates: PAPS Transport type: N/D Tissue and cellular expression: ubiquitous Subcellular expression: Golgi Disease: N/D Locus: 6p12.1-p11.2 Sequence ID: NP_835361.1, NM_178148.2 Gene ID: 347734 Splice variants: N/D

S35B2_HUMAN (UniProt)

Gene names: SLC35B2, PAPST1, PSEC0149
Protein names and data: S35B2_HUMAN, Full=Adenosine 3'-phospho 5'-phosphosulfate transporter 1, Full=PAPS transporter 1;Full=Putative MAPK-activating protein PM15;Full=Putative NF-kappa-B-activating protein 48;Full=Solute carrier family 35 member B2; Length: 432 a.a., Mass: 47515 Da,
fasta formatted sequence
Function: Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. May indirectly participate in activation of the NF- kappa-B and MAPK pathways
Cellular location: Golgi apparatus membrane; Multi-pass membrane protein
Tissue specificity: Highly expressed in the placenta, pancreas, mammary gland and skeletal muscle. Weakly or not expressed in colon, heart and prostate

Database cross-references

UniProt: Q8TB61
NextBio: 99266
OMIM: 610788
Ensembl: ENST00000393812
GeneCard: GC06M044221
TCDB: 2.A.7.11.3
PharmGenUCSF: SLC35B2
Guide to Pharmacology: SLC35B2 (1144)
SLC35 family of nucleotide sugar transporters (1144)
HGNC: HGNC:16872

Genetic variants

See also Ensembl:ENST00000393812