Protein name: CTR1 Aliases: hCtr1, Ctr1, COPT1 Substrates: copper (I), cisplatin Transport type: energy in-dependent, potassium-dependent Tissue and cellular expression: ubiquitous mRNA expression, highest in the liver, lowest in the brain, skeletal muscle Subcellular expression: protein localized plasma membrane, intracellular vesicles of cultured cells Disease: N/D Locus: 9q32 Sequence ID: NP_001850.1, NM_001859.3 Gene ID: 1317 Splice variants: N/D


Gene names: SLC31A1, COPT1, CTR1
Protein names and data: COPT1_HUMAN, Full=High affinity copper uptake protein 1, Full=Copper transporter 1;Short=hCTR1;Full=Solute carrier family 31 member 1; Length: 190 a.a., Mass: 21091 Da,
fasta formatted sequence

Function: High-affinity, saturable copper transporter involved in dietary copper uptake
Cellular location: Cell membrane; Multi-pass membrane protein. Note=Localizes to the apical membrane in intestinal epithelial cells (By similarity)

Database cross-references

UniProt: O15431
NextBio: 5387
OMIM: 603085
Ensembl: ENST00000374212
GeneCard: GC09P113221
TCDB: 1.A.56.1.2
PharmGenUCSF: SLC31A1
Guide to Pharmacology: SLC31A1 (1131)
SLC31 family of copper transporters (1131)

HGNC: HGNC:11016

Genetic variants

See also Ensembl:ENST00000374212