Protein name: N/D Aliases: ZnT7 Substrates: N/D Transport type: N/D Tissue and cellular expression: widespread, predominant intestine, stomach, prostate, retina, pancreas, testis, muscle Subcellular expression: Golgi, unknown vesicles Disease: prostate cancer, low adiposity, diet-induced diabetes Locus: N/D Sequence ID: NP_001138356.1, NM_001144884.1 NP_598003.2, NM_133496.4 Gene ID: 148867 Splice variants: N/D

ZNT7_HUMAN (UniProt)

Gene names: SLC30A7, ZNT7, ZNTL2
Protein names and data: ZNT7_HUMAN, Full=Zinc transporter 7;Short=ZnT-7, Full=Solute carrier family 30 member 7;Full=Znt-like transporter 2; Length: 376 a.a., Mass: 41626 Da,
fasta formatted sequence

Function: Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity)
Cellular location: Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein

Database cross-references

UniProt: Q8NEW0
NextBio: 86021
OMIM: 611149
Ensembl: ENST00000370112
GeneCard: GC01P100824
TCDB: 2.A.4.4.5
PharmGenUCSF: SLC30A7
Guide to Pharmacology: SLC30A7 (1127)
SLC30 zinc transporter family (1127)

HGNC: HGNC:19306

Genetic variants

See also Ensembl:ENST00000370112