Protein name: N/D Aliases: ZnT6 Substrates: N/D Transport type: N/D Tissue and cellular expression: widespread, predominant in brain, lung, intestine Subcellular expression: Golgi, unknown vesicles Disease: Alzheimer Locus: N/D Sequence ID: NP_001180442.1, NM_001193513.1 NP_001180443.1, NM_001193514.1 NP_060434.2, NM_017964.3 Gene ID: 55676 Splice variants: N/D

ZNT6_HUMAN (UniProt)

Gene names: SLC30A6, ZNT6
Protein names and data: ZNT6_HUMAN, Full=Zinc transporter 6;Short=ZnT-6, Full=Solute carrier family 30 member 6; Length: 461 a.a., Mass: 51116 Da,
fasta formatted sequence

Function: Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity)
Cellular location: Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Found in vesicles (By similarity)
Tissue specificity: Expressed in brain; especially in cerebellum, hippocampus, parahippocampal gyrus, superior and middle temporal gyrus. Also expressed in B-cells, colon, eye, and lung. Lower expression was present in bone, brain, cervix, ear, heart, kidney, muscle, nerve, pancreas, prostate, skin, stomach, and testis

Database cross-references

UniProt: Q6NXT4
NextBio: 60456
OMIM: 611148
Ensembl: ENST00000435660
GeneCard: GC02P032166
TCDB: 2.A.4.4.4
PharmGenUCSF: SLC30A6
Guide to Pharmacology: SLC30A6 (1126)
SLC30 zinc transporter family (1126)

HGNC: HGNC:19305

Genetic variants

See also Ensembl:ENST00000435660