Protein name: CNT2 Aliases: N/D Substrates: N/D Transport type: concentrative 1:1 sodium:nucleoside Tissue and cellular expression: heart, skeletal muscle, liver, kidney, intestine, pancreas, placenta, brain Subcellular expression: primarily plasma membrane-located Disease: N/D Locus: 15q15 Sequence ID: NP_004203.2, NM_004212.3 Gene ID: 9153 Splice variants: F355S, E385K

S28A2_HUMAN (UniProt)

Gene names: SLC28A2, CNT2
Protein names and data: S28A2_HUMAN, Full=Sodium/nucleoside cotransporter 2, Full=Concentrative nucleoside transporter 2;Short=CNT 2;Short=hCNT2;Full=Na(+)/nucleoside cotransporter 2;Full=Sodium-coupled nucleoside transporter 2;Full=Sodium/purine nucleoside co-transporter;Short=SPNT;Full=Solute carrier family 28 member 2; Length: 658 a.a., Mass: 71926 Da,
fasta formatted sequence

Function: Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues
Cellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung

Database cross-references

UniProt: O43868
NextBio: 34339
OMIM: 606208
Ensembl: ENST00000347644
GeneCard: GC15P045252
TCDB: 2.A.41.2.4
PharmGenUCSF: SLC28A2
Guide to Pharmacology: SLC28A2 (1115)
SLC28 family (1115)

HGNC: HGNC:11002

Genetic variants

See also Ensembl:ENST00000347644