SLC26A6

Protein name: CFEX, PAT1, SLC26A6 Aliases: N/D Substrates: Cl-, HCO3-, oxalate, OH-, formate Transport type: Exchanger / Cl-, HCO3-, oxalate, OH-, formate Tissue and cellular expression: enterocytes, pancreatic duct, renal prox tubule, cardiac myocytes, sperm Subcellular expression: N/D Disease: (grossly normal: loss or reduction of cAMP-stimulated HCO3-secretion in GI epithelia) Locus: 3p21.3 Sequence ID: NP_075062.2, NM_022911.2 NP_599025.2, NM_134263.2 NP_602298.2, NM_134426.2 Gene ID: 65010 Splice variants: 4 mRNAs, 4 ORFs

S26A6_HUMAN (UniProt)

Gene names: SLC26A6
Protein names and data: S26A6_HUMAN, Full=Solute carrier family 26 member 6, Full=Pendrin-like protein 1;Short=Pendrin-L1; Length: 759 a.a., Mass: 82967 Da,
fasta formatted sequence
Function: Does not seem to be involved in anion transport
Cellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Ubiquitous. Highest levels in kidney and pancreas. Lower expression in heart, skeletal muscle, liver and placenta. Also found in lung and brain

Database cross-references

UniProt: Q9BXS9
NextBio: 67202
OMIM: 610068
Ensembl: ENST00000420764
GeneCard: GC03M048625
TCDB: 2.A.53.2.7
PharmGenUCSF: SLC26A6
Guide to Pharmacology: SLC26A6 (1101)
Chloride/bicarbonate exchangers (1101)
HGNC: HGNC:14472

Genetic variants

See also Ensembl:ENST00000420764