Protein name: DRA, CLD, SLC26A3 Aliases: N/D Substrates: Cl-, HCO3-, oxalate Transport type: Exchanger / Cl-, HCO3-, oxalate Tissue and cellular expression: enterocytes, sperrm, epididymis Subcellular expression: apical Disease: congenital chloride diarrhea Locus: 7q31 Sequence ID: NP_000102.1, NM_000111.2 Gene ID: 1811 Splice variants: 1 mRNA, 1 ORF

S26A3_HUMAN (UniProt)

Gene names: SLC26A3, DRA
Protein names and data: S26A3_HUMAN, Full=Chloride anion exchanger, Full=Down-regulated in adenoma;Short=Protein DRA;Full=Solute carrier family 26 member 3; Length: 764 a.a., Mass: 84505 Da,
fasta formatted sequence

Function: Chloride/bicarbonate exchanger. Mediates the efficient absorbtion of chloride ions in the colon, participating in fluid homeostasis
Cellular location: Apical cell membrane; Multi-pass membrane protein

Database cross-references

UniProt: P40879
NextBio: 7381
OMIM: 126650 214700
Ensembl: ENST00000340010
GeneCard: GC07M107765
PharmGenUCSF: SLC26A3
Guide to Pharmacology: SLC26A3 (1099)
Chloride/bicarbonate exchangers (1099)


Genetic variants

See also Ensembl:ENST00000340010