SLC26A11

Protein name: SUT1, KBAT, SLC26A11 Aliases: N/D Substrates: Cl-, HCO3-, SO42-, oxalate (?), Ch: Cl- Transport type: Exchanger / Cl-, HCO3-, SO42-, oxalate, ?Ch / Cl- Tissue and cellular expression: renal intercalated cells, panc duct, endothelial cells, brain, widespread Subcellular expression: apical (renal intercalated cells) Disease: not reported Locus: 17q25.3 Sequence ID: NP_001159819.1, NM_001166347.1 NP_001159820.1, NM_001166348.1 NP_001159821.1, NM_001166349.1 NP_775897.3, NM_173626.3 Gene ID: 284129 Splice variants: 4 mRNAs, 1 ORF

S2611_HUMAN (UniProt)

Gene names: SLC26A11
Protein names and data: S2611_HUMAN, Full=Sodium-independent sulfate anion transporter, Full=Solute carrier family 26 member 11; Length: 606 a.a., Mass: 65299 Da,
fasta formatted sequence

Function: Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC)
Cellular location: Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein
Tissue specificity: Detected in all tissues tested with highest expression observed in brain, kidney, HEVEC and placenta and lowest in pancreas, skeletal muscle, liver, lung and heart

Database cross-references

UniProt: Q86WA9
NextBio: 94576
OMIM: 610117
Ensembl: ENST00000572725
GeneCard: GC17P080219
PharmGenUCSF: SLC26A11
Guide to Pharmacology: SLC26A11 (1107)
Other SLC26 anion exchangers (1107)

HGNC: HGNC:14471

Genetic variants

See also Ensembl:ENST00000572725