Protein name: SAT1, SLC26A1 Aliases: N/D Substrates: SO42-, oxalate, glyoxylate Transport type: Exchanger / SO42-, oxalate, glyoxylate Tissue and cellular expression: hepatocytes, renal prox tubule, intestine Subcellular expression: basolateral Disease: (oxalate urolithiasis, nephrocalcinosis, urinary sulfate wasting, hepatotoxicity) Locus: 4p16.3 Sequence ID: NP_071325.2, NM_022042.2 NP_602297.1, NM_134425.1 NP_998778.1, NM_213613.2 Gene ID: 10861 Splice variants: 3 mRNAs, 2 ORFs

S26A1_HUMAN (UniProt)

Gene names: SLC26A1, SAT1
Protein names and data: S26A1_HUMAN, Full=Sulfate anion transporter 1;Short=SAT-1, Full=Solute carrier family 26 member 1; Length: 701 a.a., Mass: 75016 Da,
fasta formatted sequence

Function: High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate
Cellular location: Membrane; Multi-pass membrane protein (By similarity)
Tissue specificity: Expressed most abundantly in the kidney and liver, with lower levels in the pancreas, testis, brain, small intestine, colon, and lung

Database cross-references

UniProt: Q9H2B4
NextBio: 41233
OMIM: 610130
Ensembl: ENST00000398520
GeneCard: GC04M000962
PharmGenUCSF: SLC26A1
Guide to Pharmacology: SLC26A1 (1097)
Selective sulphate transporters (1097)

HGNC: HGNC:10993

Genetic variants

See also Ensembl:ENST00000398520