Protein name: AAC4, ANT4 (adenine nucleotide carrier 4) Aliases: SFEC Substrates: ADP, ATP Transport type: Exchanger / ADP, ATP Tissue and cellular expression: testis Subcellular expression: N/D Disease: (sperato-genesis) Locus: 4q28.1 Sequence ID: NP_112581.1, NM_031291.2 Gene ID: 83447 Splice variants: N/D

ADT4_HUMAN (UniProt)

Gene names: SLC25A31, AAC4, ANT4, SFEC
Protein names and data: ADT4_HUMAN, Full=ADP/ATP translocase 4, Full=ADP,ATP carrier protein 4;Full=Adenine nucleotide translocator 4;Short=ANT 4;Full=Solute carrier family 25 member 31;Full=Sperm flagellar energy carrier protein; Length: 315 a.a., Mass: 35022 Da,
fasta formatted sequence

Function: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility
Cellular location: Mitochondrion inner membrane; Multi-pass membrane protein. Cell projection, cilium, flagellum. Note=In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region
Tissue specificity: Expressed in brain, liver, sperm and testis

Database cross-references

UniProt: Q9H0C2
NextBio: 72348
OMIM: 610796
Ensembl: ENST00000281154
GeneCard: GC04P127730
TCDB: 2.A.29.1.8
PharmGenUCSF: SLC25A31
Guide to Pharmacology: SLC25A31 (1065)
Mitochondrial nucleotide transporter subfamily (1065)

HGNC: HGNC:25319

Genetic variants

See also Ensembl:ENST00000281154