Protein name: CAC (carnitine / acylcarnitine carrier) Aliases: CACT, carnitine carrier Substrates: carnitine, acylcarnitine Transport type: Exchanger / carnitine, acylcarnitine; F (at slow rate) Tissue and cellular expression: heart, skeletal muscle, liver, also in lung, kidney, brain, pancreas, lung, placenta Subcellular expression: inner mitochondrial membrane Disease: carnitine acylcarnitine carrier deficiency Locus: 3p21.31 Sequence ID: NP_000378.1, NM_000387.5 Gene ID: 788 Splice variants: N/D


Gene names: SLC25A20, CAC, CACT
Protein names and data: MCAT_HUMAN, Full=Mitochondrial carnitine/acylcarnitine carrier protein, Full=Carnitine/acylcarnitine translocase;Short=CAC;Full=Solute carrier family 25 member 20; Length: 301 a.a., Mass: 32944 Da,
fasta formatted sequence

Function: Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway
Cellular location: Mitochondrion inner membrane; Multi-pass membrane protein

Database cross-references

UniProt: O43772
NextBio: 3206
OMIM: 212138 613698
Ensembl: ENST00000319017
GeneCard: GC03M048869
TCDB: 2.A.29.8.3
PharmGenUCSF: SLC25A20
Guide to Pharmacology: SLC25A20 (1076)
Mitochondrial amino acid transporter subfamily (1076)


Genetic variants

See also Ensembl:ENST00000319017