Protein name: ORC1 (ornithine carrier 1) Aliases: ORNT1, HHH Substrates: ornithine, citrulline, lysine, arginine Transport type: Exchanger / ornithine, citrulline, H+; ornithine, H+ Tissue and cellular expression: liver, pancreas, lung, testis, small intestine, spleen, kidney, brain, heart Subcellular expression: inner mitochondrial membrane Disease: hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome Locus: 13q14.11 Sequence ID: NP_055067.1, NM_014252.3 Gene ID: 10166 Splice variants: N/D


Gene names: SLC25A15, ORNT1, SP1855
Protein names and data: ORNT1_HUMAN, Full=Mitochondrial ornithine transporter 1, Full=Solute carrier family 25 member 15; Length: 301 a.a., Mass: 32736 Da,
fasta formatted sequence

Function: Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix
Cellular location: Mitochondrion inner membrane; Multi-pass membrane protein

Database cross-references

UniProt: Q9Y619
NextBio: 38490
OMIM: 238970 603861
Ensembl: ENST00000426521
GeneCard: GC13P040789
TCDB: 2.A.29.19.2
PharmGenUCSF: SLC25A15
Guide to Pharmacology: SLC25A15 (1060)
Mitochondrial amino acid transporter subfamily (1060)

HGNC: HGNC:10985

Genetic variants

See also Ensembl:ENST00000426521