Protein name: DIC (dicarboxylate carrier) Aliases: N/D Substrates: malate, phosphate, succinate, sulphate, thiosulphate Transport type: Exchanger / malate, phosphate Tissue and cellular expression: liver, kidney, heart, brain, lung, pancreas Subcellular expression: inner mitochondrial membrane Disease: N/D Locus: 17q25.3 Sequence ID: NP_001257817.1, NP_036272.2, NM_012140.3 Gene ID: 1468 Splice variants: N/D


Gene names: SLC25A10, DIC
Protein names and data: DIC_HUMAN, Full=Mitochondrial dicarboxylate carrier, Full=Solute carrier family 25 member 10; Length: 287 a.a., Mass: 31282 Da,
fasta formatted sequence

Function: Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane
Cellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Tissue specificity: Present in high amounts in liver and kidney, and at lower levels in all the other tissues analyzed

Database cross-references

UniProt: Q9UBX3
NextBio: 6027
OMIM: 606794
Ensembl: ENST00000350690
GeneCard: GC17P081712
TCDB: 2.A.29.2.7
PharmGenUCSF: SLC25A10
Guide to Pharmacology: SLC25A10 (1052)
Mitochondrial di- and tri-carboxylic acid transporter subfamily (1052)

HGNC: HGNC:10980

Genetic variants

See also Ensembl:ENST00000350690