Protein name: OAT4 Aliases: N/D Substrates: organic anions Transport type: Facilitated transporter or E Tissue and cellular expression: kidney, placenta Subcellular expression: luminal membrane of proximal tubules (kidney) Disease: Reduced plasma uric acid level Locus: 11q13.1 Sequence ID: NP_060954.1, NM_018484.2 Gene ID: 55867 Splice variants: N/D

S22AB_HUMAN (UniProt)

Gene names: SLC22A11, OAT4
Protein names and data: S22AB_HUMAN, Full=Solute carrier family 22 member 11, Full=Organic anion transporter 4; Length: 550 a.a., Mass: 59972 Da,
fasta formatted sequence

Function: Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds
Cellular location: Cell membrane; Multi-pass membrane protein
Tissue specificity: Detected in placenta and kidney

Database cross-references

UniProt: Q9NSA0
NextBio: 61178
OMIM: 607097
Ensembl: ENST00000377585
GeneCard: GC11P064573
TCDB: 2.A.1.19.10
PharmGenUCSF: SLC22A11
Guide to Pharmacology: SLC22A11 (1030)
Organic anion transporters (OATs) (1030)

HGNC: HGNC:18120

Genetic variants

See also Ensembl:ENST00000377585