SLC17A1

Protein name: NPT1 Aliases: NaPi1 Substrates: organic anions, phosphate, chloride Transport type: electrogenic, Cl- dependent; C/Na+; channel Tissue and cellular expression: kidney, liver Subcellular expression: plasma membrane Disease: gout Locus: 6p22.2, Sequence ID: NP_005065.2, NM_005074.3 Gene ID: 6568 Splice variants: N/D

NPT1_HUMAN (UniProt)

Gene names: SLC17A1, NPT1
Protein names and data: NPT1_HUMAN, Full=Sodium-dependent phosphate transport protein 1, Full=Na(+)/PI cotransporter 1;Full=Na/Pi-4;Full=Renal Na(+)-dependent phosphate cotransporter 1;Full=Renal sodium-dependent phosphate transport protein 1;Short=Renal sodium-phosphate transport protein 1;Full=Sodium/phosphate cotransporter 1;Full=Solute carrier family 17 member 1; Length: 467 a.a., Mass: 51132 Da,
fasta formatted sequence
Function: Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane
Cellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Expressed in kidney cortex, liver and brain but not in other tissues

Database cross-references

UniProt: Q14916
NextBio: 25555
OMIM: 182308
Ensembl: ENST00000476801
GeneCard: GC06M025785
PharmGenUCSF: SLC17A1
Guide to Pharmacology: SLC17A1 (1002)
Type I sodium-phosphate co-transporters (1002)
HGNC: HGNC:10929

Genetic variants

See also Ensembl:ENST00000476801