Protein name: TAT1, MCT10 Aliases: MOT10 Substrates: aromatic amino acids, T3, T4 Transport type: Facilitated transporter Tissue and cellular expression: kidney, intestine, muscle, placenta, heart Subcellular expression: basolateral (kidney) Disease: N/D Locus: 6q21-q22 Sequence ID: NP_061063.2, NM_018593.4 Gene ID: 117247 Splice variants: several splice variants listed in ENSG00000112394

MOT10_HUMAN (UniProt)

Gene names: SLC16A10, MCT10, TAT1
Protein names and data: MOT10_HUMAN, Full=Monocarboxylate transporter 10;Short=MCT 10, Full=Aromatic amino acid transporter 1;Full=Solute carrier family 16 member 10;Full=T-type amino acid transporter 1; Length: 515 a.a., Mass: 55493 Da,
fasta formatted sequence

Function: Sodium-independent transporter that mediates the update of aromatic acid. Can function as a net efflux pathway for aromatic amino acids in the basosolateral epithelial cells (By similarity)
Cellular location: Cell membrane; Multi-pass membrane protein (By similarity). Basolateral cell membrane (By similarity)
Tissue specificity: Strongly expressed in kidney and skeletal muscle and at lower level in placenta and heart

Database cross-references

UniProt: Q8TF71
NextBio: 80178
OMIM: 607550
Ensembl: ENST00000368851
GeneCard: GC06P111087
TCDB: 2.A.1.13.8
PharmGenUCSF: SLC16A10
Guide to Pharmacology: SLC16A10 (993)
SLC16 family of monocarboxylate transporters (993)

HGNC: HGNC:17027

Genetic variants

See also Ensembl:ENST00000368851