Protein name: N/D Aliases: UT1 Substrates: N/D Transport type: N/D Tissue and cellular expression: inner medullary collecting duct, cochlea Subcellular expression: luminal membrane (kidney) Disease: N/D Locus: N/D Sequence ID: NP_001229621.1, NP_009094.3, Gene ID: 8170 Splice variants: N/D

UT2_HUMAN (UniProt)

Gene names: SLC14A2, HUT2, UT2
Protein names and data: UT2_HUMAN, Full=Urea transporter 2, Full=Solute carrier family 14 member 2;Full=Urea transporter, kidney; Length: 920 a.a., Mass: 101209 Da,
fasta formatted sequence

Function: Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism
Cellular location: Apical cell membrane; Multi-pass membrane protein
Tissue specificity: Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney

Database cross-references

UniProt: Q15849
NextBio: 30845
OMIM: 601611
Ensembl: ENST00000255226
GeneCard: GC18P045212
PharmGenUCSF: SLC14A2
Guide to Pharmacology: SLC14A2_UT-A1 (983)
SLC14 family of facilitative urea transporters (983)

HGNC: HGNC:10919

Genetic variants

See also Ensembl:ENST00000255226