Protein name: NTCP Aliases: LBAT Substrates: bile acids Transport type: Cotransporter / Na+ Tissue and cellular expression: liver, pancreas Subcellular expression: basolateral (liver) Disease: N/D Locus: 14q24.1 Sequence ID: NP_003040.1, NM_003049.3 Gene ID: 6554 Splice variants: N/D


Gene names: SLC10A1, NTCP, GIG29
Protein names and data: NTCP_HUMAN, Full=Sodium/bile acid cotransporter, Full=Cell growth-inhibiting gene 29 protein;Full=Na(+)/bile acid cotransporter;Full=Na(+)/taurocholate transport protein;Full=Sodium/taurocholate cotransporting polypeptide;Full=Solute carrier family 10 member 1; Length: 349 a.a., Mass: 38119 Da,
fasta formatted sequence

Function: The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium
Cellular location: Membrane; Multi-pass membrane protein

Database cross-references

UniProt: Q14973
NextBio: 25503
OMIM: 182396
Ensembl: ENST00000216540
GeneCard: GC14M069775
PharmGenUCSF: SLC10A1
Guide to Pharmacology: SLC10A1 (959)
SLC10 family of sodium-bile acid co-transporters (959)

HGNC: HGNC:10905

Genetic variants

See also Ensembl:ENST00000216540