SLC9A5

Protein name: NHE5 Aliases: N/D Substrates: Na+, Li+, H+, NH4+ (?) Transport type: Exchanger / Na+, H+ Tissue and cellular expression: Brain Subcellular expression: N/D Disease: N/D Locus: 16q22.1 Sequence ID: NP_004585.1, NM_004594.2 Gene ID: 6553 Splice variants: N/D

SL9A5_HUMAN (UniProt)

Gene names: SLC9A5, NHE5
Protein names and data: SL9A5_HUMAN, Full=Sodium/hydrogen exchanger 5, Full=Na(+)/H(+) exchanger 5;Short=NHE-5;Full=Solute carrier family 9 member 5; Length: 896 a.a., Mass: 99011 Da,
fasta formatted sequence
Function: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction (By similarity)
Cellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Expressed in brain, testis, spleen, and skeletal muscle

Database cross-references

UniProt: Q14940
NextBio: 25499
OMIM: 600477
Ensembl: ENST00000299798
GeneCard: GC16P067282
PharmGenUCSF: SLC9A5
Guide to Pharmacology: SLC9A5 (952)
SLC9 family of sodium/hydrogen exchangers (952)
HGNC: HGNC:11078

Genetic variants

See also Ensembl:ENST00000299798