Protein name: Asc-1 Aliases: [4F2hc], system asc Substrates: small neutral amino acids Transport type: preferentially E Tissue and cellular expression: brain, CNS, lung, small intestine, heart, placenta, skeletal muscle, kidney Subcellular expression: N/D Disease: N/D Locus: 19q13.1 Sequence ID: NP_062823.1, NM_019849.2 Gene ID: 56301 Splice variants: N/D

AAA1_HUMAN (UniProt)

Gene names: SLC7A10, ASC1
Protein names and data: AAA1_HUMAN, Full=Asc-type amino acid transporter 1;Short=Asc-1, Full=Solute carrier family 7 member 10; Length: 523 a.a., Mass: 56798 Da,
fasta formatted sequence

Function: Sodium-independent, high affinity transport of small neutral D- and L-amino acids. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse
Cellular location: Membrane; Multi-pass membrane protein (Probable)
Tissue specificity: Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle

Database cross-references

UniProt: Q9NS82
NextBio: 61967
OMIM: 607959
Ensembl: ENST00000253188
GeneCard: GC19M033208
PharmGenUCSF: SLC7A10
Guide to Pharmacology: SLC7A10 (901)
SLC7 family (901)

HGNC: HGNC:11058

Genetic variants

See also Ensembl:ENST00000253188