SLC6A9

Protein name: N/D Aliases: GlyT1 Substrates: glycine Transport type: N/D Tissue and cellular expression: brain, retina, liver, spleen, kidney, pancreas, uterus, stomach, lung, placenta, intestine Subcellular expression: N/D Disease: schizophrenia Locus: 1p33 Sequence ID: NP_001020016.1, NM_001024845.1 NP_008865.2, NM_006934.2 NP_964012.2, NM_201649.2 Gene ID: 6536 Splice variants: N/D

SC6A9_HUMAN (UniProt)

Gene names: SLC6A9
Protein names and data: SC6A9_HUMAN, Full=Sodium- and chloride-dependent glycine transporter 1;Short=GlyT-1;Short=GlyT1, Full=Solute carrier family 6 member 9; Length: 706 a.a., Mass: 78260 Da,
fasta formatted sequence
Function: Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission
Cellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Isoform GlyT-1A and isoform GlyT-1B can be found in brain, kidney, pancreas, lung, placenta and liver but isoform GlyT-1C is only found in brain

Database cross-references

UniProt: P48067
NextBio: 25431
OMIM: 601019
Ensembl: ENST00000372310
GeneCard: GC01M043991
PharmGenUCSF: SLC6A9
Guide to Pharmacology: SLC6A9 (935)
Glycine transporter subfamily (935)
HGNC: HGNC:11056

Genetic variants

See also Ensembl:ENST00000372310