Protein name: N/D Aliases: TauT Substrates: taurine Transport type: N/D Tissue and cellular expression: brain, retina, liver, kidney, heart, spleen, pancreas, placenta, skeletal muscle, lung Subcellular expression: N/D Disease: taurine deficiency diseases, retinal blindness, abnormal renal development Locus: 3p25-p24 Sequence ID: NP_001127839.1, NM_001134367.1 NP_003034.2, NM_003043.3 Gene ID: 6533 Splice variants: N/D

SC6A6_HUMAN (UniProt)

Gene names: SLC6A6
Protein names and data: SC6A6_HUMAN, Full=Sodium- and chloride-dependent taurine transporter, Full=Solute carrier family 6 member 6; Length: 620 a.a., Mass: 69830 Da,
fasta formatted sequence

Function: Required for the uptake of taurine. Transports both taurine and beta-alanine which requires sodium ions. Chloride ions are necessary for optimal uptake
Cellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver

Database cross-references

UniProt: P31641
NextBio: 25419
OMIM: 186854
Ensembl: ENST00000454876
GeneCard: GC03P014402
TCDB: 2.A.22.3.3
PharmGenUCSF: SLC6A6
Guide to Pharmacology: SLC6A6 (933)
GABA transporter subfamily (933)

HGNC: HGNC:11052

Genetic variants

See also Ensembl:ENST00000454876