Protein name: N/D Aliases: system IMINO, XT3, Xtrp3 Substrates: proline, pipecolate, sarcosine Transport type: N/D Tissue and cellular expression: brain, kidney, small intestine, thymus, spleen, ovary, lung Subcellular expression: N/D Disease: iminoglycinuria Locus: 3p21.3 Sequence ID: NP_064593.1, NM_020208.3 NP_071800.1, NM_022405.3 Gene ID: 54716 Splice variants: N/D

S6A20_HUMAN (UniProt)

Gene names: SLC6A20, SIT1, XT3, XTRP3
Protein names and data: S6A20_HUMAN, Full=Sodium- and chloride-dependent transporter XTRP3, Full=Sodium/imino-acid transporter 1;Full=Solute carrier family 6 member 20;Full=Transporter rB21A homolog; Length: 592 a.a., Mass: 65914 Da,
fasta formatted sequence

Function: Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N- methylated amino acids. Involved in the transport of glycine
Cellular location: Apical cell membrane; Multi-pass membrane protein (By similarity). Note=Located in the apical brush border membrane of kidney proximal tubule cells (By similarity)
Tissue specificity: Kidney and small intestine. Expressed in the S3 segment of the proximal tubule

Database cross-references

UniProt: Q9NP91
NextBio: 57286
OMIM: 138500 242600 605616
Ensembl: ENST00000358525
GeneCard: GC03M045796
PharmGenUCSF: SLC6A20
Guide to Pharmacology: SLC6A20 (944)
Neutral amino acid transporter subfamily (944)

HGNC: HGNC:30927

Genetic variants

See also Ensembl:ENST00000358525