SLC6A11

Protein name: N/D Aliases: GAT-B, GAT-3 Substrates: GABA Transport type: N/D Tissue and cellular expression: brain (GABAergic neurons, glia) Subcellular expression: N/D Disease: epilepsy Locus: 3p25.3 Sequence ID: NP_055044.1, NM_014229.1 Gene ID: 6538 Splice variants: N/D

S6A11_HUMAN (UniProt)

Gene names: SLC6A11, GABT3, GAT3
Protein names and data: S6A11_HUMAN, Full=Sodium- and chloride-dependent GABA transporter 3;Short=GAT-3, Full=Solute carrier family 6 member 11; Length: 632 a.a., Mass: 70606 Da,
fasta formatted sequence

Function: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals
Cellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Widespread distribution in the brain

Database cross-references

UniProt: P48066
NextBio: 25439
OMIM: 607952
Ensembl: ENST00000254488
GeneCard: GC03P010857
PharmGenUCSF: SLC6A11
Guide to Pharmacology: SLC6A11 (931)
GABA transporter subfamily (931)

HGNC: HGNC:11044

Genetic variants

See also Ensembl:ENST00000254488