Protein name: LAT4 Aliases: N/D Substrates: L-BCAAs, amino alcohols Transport type: Facilitated transporter Tissue and cellular expression: placenta, kidney, peripheral blood leukocytes, small intestine Subcellular expression: N/D Disease: N/D Locus: 17p13.3 Sequence ID: NP_689559.1, NM_152346.1 Gene ID: 124935 Splice variants: N/D

LAT4_HUMAN (UniProt)

Gene names: SLC43A2, LAT4, PP7664
Protein names and data: LAT4_HUMAN, Full=Large neutral amino acids transporter small subunit 4, Full=L-type amino acid transporter 4;Full=Solute carrier family 43 member 2; Length: 569 a.a., Mass: 62747 Da,
fasta formatted sequence

Function: Sodium-, chloride-, and pH-independent high affinity transport of large neutral amino acids
Cellular location: Membrane; Multi-pass membrane protein (By similarity)
Tissue specificity: Detected in several tissues with higher expression in placenta, kidney and peripheral blood leukocytes. In the kidney, is detected in epithelial cells of the distal tubule and collecting duct. In the intestine, is expressed mainly in crypt cells of the intestinal microvilli and epithelial cells in the base of the villus

Database cross-references

UniProt: Q8N370
NextBio: 81433
OMIM: 610791
Ensembl: ENST00000571650
GeneCard: GC17M001572
TCDB: 2.A.1.44.2
PharmGenUCSF: SLC43A2
Guide to Pharmacology: SLC43A2 (1202)
SLC43 family of large neutral amino acid transporters (1202)

HGNC: HGNC:23087

Genetic variants

See also Ensembl:ENST00000571650