Protein name: ZIP2, Eti-1, 6A1 Aliases: N/D Substrates: Zn Transport type: N/D Tissue and cellular expression: widespread Subcellular expression: plasma membrane Disease: N/D Locus: 14q11.1 Sequence ID: NP_055394.2, NM_014579.3 Gene ID: 29986 Splice variants: N/D

S39A2_HUMAN (UniProt)

Gene names: SLC39A2, ZIP2
Protein names and data: S39A2_HUMAN, Full=Zinc transporter ZIP2, Full=6A1;Full=Eti-1;Full=Solute carrier family 39 member 2;Full=Zrt- and Irt-like protein 2;Short=ZIP-2;Short=hZIP2; Length: 309 a.a., Mass: 32742 Da,
fasta formatted sequence

Function: Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis
Cellular location: Cell membrane; Multi-pass membrane protein
Tissue specificity: Expressed only in prostate and uterine epithelial cells

Database cross-references

UniProt: Q9NP94
NextBio: 52756
OMIM: 612166
Ensembl: ENST00000298681
GeneCard: GC14P021054
TCDB: 2.A.5.3.1
PharmGenUCSF: SLC39A2
Guide to Pharmacology: SLC39A2 (1181)
SLC39 family of metal ion transporters (1181)

HGNC: HGNC:17127

Genetic variants

See also Ensembl:ENST00000298681