Protein name: GLUT1 Aliases: N/D Substrates: glucose, galactose, mannose, glucosamine Transport type: Facilitated transporter Tissue and cellular expression: erythrocytes, brain, blood-brain barrier, blood-tissue barrier, many fetal tissues Subcellular expression: N/D Disease: paroxysmal exertion-induced dyskinesia, dystonia-18, Glut1 deficiency syndrome Locus: 1p35-31.3 Sequence ID: NP_006507.2, NM_006516.2 Gene ID: 6513 Splice variants: N/D

GTR1_HUMAN (UniProt)

Gene names: SLC2A1, GLUT1
Protein names and data: GTR1_HUMAN, Full=Solute carrier family 2, facilitated glucose transporter member 1, Full=Glucose transporter type 1, erythrocyte/brain;Short=GLUT-1;Full=HepG2 glucose transporter; Length: 492 a.a., Mass: 54084 Da,
fasta formatted sequence

Function: Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses
Cellular location: Cell membrane; Multi-pass membrane protein (By similarity). Melanosome. Note=Localizes primarily at the cell surface (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Tissue specificity: Expressed at variable levels in many human tissues

Database cross-references

UniProt: P11166
NextBio: 25327
OMIM: 138140 606777 612126
Ensembl: ENST00000426263
GeneCard: GC01M042925
TCDB: 2.A.1.1.28
PharmGenUCSF: SLC2A1
Guide to Pharmacology: SLC2A1 (875)
Class I transporters (875)

HGNC: HGNC:11005

Genetic variants

See also Ensembl:ENST00000426263