SLC27A6

Protein name: FATP6 Aliases: ACSVL2, VLCS-H1, FACVL2 Substrates: LCFA, VLCFA Transport type: LCFA transport, VLCFA activation Tissue and cellular expression: heart, skin Subcellular expression: N/D Disease: unknown Locus: 5q23.3 Sequence ID: NP_001017372.1, NM_001017372.1 NP_054750.1, NM_014031.3 Gene ID: 28965 Splice variants: variant 2 has an additional segment in the 5' UTR but encodes the same protein as variant 1

S27A6_HUMAN (UniProt)

Gene names: SLC27A6, ACSVL2, FACVL2, FATP1
Protein names and data: S27A6_HUMAN, Full=Long-chain fatty acid transport protein 6;Short=FATP-6;Short=Fatty acid transport protein 6, Full=Fatty-acid-coenzyme A ligase, very long-chain 2;Full=Solute carrier family 27 member 6;Full=Very long-chain acyl-CoA synthetase homolog 1;Short=VLCSH1;Short=hVLCS-H1; Length: 619 a.a., Mass: 70112 Da,
fasta formatted sequence
Function: Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Thought to function as the predominant fatty acid protein transporter in heart
Cellular location: Membrane; Multi-pass membrane protein (Potential). Cell membrane, sarcolemma (By similarity). Note=In heart is exclusively located on the sarcolemma in areas juxtaposed with small blood vessels where it colocalizes CD36 (By similarity)
Tissue specificity: Strongly expressed in heart and localizes to cardiac myocytes. Expressed at moderate levels in placenta, testis, and adrenal glands. Expressed at very low levels in kidney, bladder and uterus

Database cross-references

UniProt: Q9Y2P4
NextBio: 51813
OMIM: 604196
Ensembl: ENST00000506176
GeneCard: GC05P128538
PharmGenUCSF: SLC27A6
Guide to Pharmacology: SLC27A6 (1113)
SLC27 family of fatty acid transporters (1113)
HGNC: HGNC:11000

Genetic variants

See also Ensembl:ENST00000506176