Protein name: ANT3 (adenine nucleotide translocase-3) Aliases: AAC3, T3 Substrates: ADP, ATP Transport type: Exchanger / ADP, ATP Tissue and cellular expression: brain, lung, kidney, liver, pancreas, heart, skeletal muscle, spleen, thymus Subcellular expression: inner mitochondrial membrane Disease: N/D Locus: Xp22.32, Yp11.3 Sequence ID: NP_001627.2, NM_001636.3 Gene ID: 293 Splice variants: N/D

ADT3_HUMAN (UniProt)

Gene names: SLC25A6, ANT3, CDABP0051
Protein names and data: ADT3_HUMAN, Full=ADP/ATP translocase 3, Full=ADP,ATP carrier protein 3;Full=ADP,ATP carrier protein, isoform T2;Short=ANT 2;Full=Adenine nucleotide translocator 3;Short=ANT 3;Full=Solute carrier family 25 member 6; Length: 298 a.a., Mass: 32866 Da,
fasta formatted sequence

Function: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis
Cellular location: Mitochondrion inner membrane; Multi-pass membrane protein. Note=The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria (By similarity)

Database cross-references

UniProt: P12236
NextBio: 1195
OMIM: 300151 403000
Ensembl: ENST00000381401
GeneCard: GC0XM001386
PharmGenUCSF: SLC25A6
Guide to Pharmacology: SLC25A6 (1064)
Mitochondrial nucleotide transporter subfamily (1064)

HGNC: HGNC:10992

Genetic variants

See also Ensembl:ENST00000381401