Protein name: ANT2 (adenine nucleotide translocase-2) Aliases: AAC2, T2 Substrates: ADP, ATP Transport type: Exchanger / ADP, ATP Tissue and cellular expression: brain, lung, kidney, pancreas, heart, skeletal muscle, spleen Subcellular expression: inner mitochondrial membrane Disease: N/D Locus: Xq24-Xq26 Sequence ID: NP_001143.2, NM_001152.4 Gene ID: 292 Splice variants: N/D

ADT2_HUMAN (UniProt)

Gene names: SLC25A5, ANT2
Protein names and data: ADT2_HUMAN, Full=ADP/ATP translocase 2, Full=ADP,ATP carrier protein 2;Full=ADP,ATP carrier protein, fibroblast isoform;Full=Adenine nucleotide translocator 2;Short=ANT 2;Full=Solute carrier family 25 member 5; Length: 298 a.a., Mass: 32852 Da,
fasta formatted sequence

Function: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation
Cellular location: Mitochondrion inner membrane; Multi-pass membrane protein

Database cross-references

UniProt: P05141
NextBio: 1191
OMIM: 300150
Ensembl: ENST00000317881
GeneCard: GC0XP119468
TCDB: 2.A.29.1.1
PharmGenUCSF: SLC25A5
Guide to Pharmacology: SLC25A5 (1063)
Mitochondrial nucleotide transporter subfamily (1063)

HGNC: HGNC:10991

Genetic variants

See also Ensembl:ENST00000317881