Protein name: SAMC Aliases: N/D Substrates: S-adenosyl-methionine, S-adenosyl-homocysteine Transport type: Exchanger / S-adenosyl-methionine, S-adenosyl-homocysteine Tissue and cellular expression: ubiquitous (testis) Subcellular expression: inner mitochondrial membrane Disease: N/D Locus: 3p14.1 Sequence ID: NP_001158268.1, NM_001164796.1 NP_775742.4, NM_173471.3 Gene ID: 115286 Splice variants: N/D


Gene names: SLC25A26, SAMC
Protein names and data: SAMC_HUMAN, Full=S-adenosylmethionine mitochondrial carrier protein, Full=Mitochondrial S-adenosylmethionine transporter;Full=Solute carrier family 25 member 26; Length: 274 a.a., Mass: 29381 Da,
fasta formatted sequence

Function: Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Specifically mediates the transport of S- adenosylmethionine (SAM) into the mitochondria
Cellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Tissue specificity: Widely expressed. Highly expressed in testis, with moderate expression in brain, heart, kidney, lung, skeletal muscle, pancreas, small intestine and liver, and low expression in spleen

Database cross-references

UniProt: Q70HW3
NextBio: 79552
OMIM: 611037
Ensembl: ENST00000336733
GeneCard: GC03P066120
PharmGenUCSF: SLC25A26
Guide to Pharmacology: SLC25A26 (1074)
Mitochondrial nucleotide transporter subfamily (1074)

HGNC: HGNC:20661

Genetic variants

See also Ensembl:ENST00000336733