Protein name: ODC (oxoadipate carrier) Aliases: N/D Substrates: oxoadipate, oxoglutarate Transport type: Exchanger / oxoadipate, oxoglutarate Tissue and cellular expression: kidney, gall bladder, colon, liver, placenta, testis, lung, spleen, skeletal muscle, brain, heart Subcellular expression: inner mitochondrial membrane Disease: N/D Locus: 14q11.2 Sequence ID: NP_001164641.1, NM_001171170.1 NP_085134.1, NM_030631.3 Gene ID: 89874 Splice variants: N/D


Gene names: SLC25A21, ODC
Protein names and data: ODC_HUMAN, Full=Mitochondrial 2-oxodicarboxylate carrier, Full=Solute carrier family 25 member 21; Length: 299 a.a., Mass: 33303 Da,
fasta formatted sequence

Function: Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate
Cellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Tissue specificity: Ubiquitous

Database cross-references

UniProt: Q9BQT8
NextBio: 76380
OMIM: 607571
Ensembl: ENST00000331299
GeneCard: GC14M036677
TCDB: 2.A.29.2.4
PharmGenUCSF: SLC25A21
Guide to Pharmacology: SLC25A21 (1057)
Mitochondrial di- and tri-carboxylic acid transporter subfamily (1057)

HGNC: HGNC:14411

Genetic variants

See also Ensembl:ENST00000331299