SLC24A4
Protein name: NCKX4 Aliases: SHEP6, FLJ38852 Substrates: Na+, Ca2+, K+ Transport type: Exchanger / 4 Na+, Ca2+, K+ Tissue and cellular expression: brain, olfactory neurons, aorta, lung, thymus Subcellular expression: plasma membrane Disease: N/D Locus: 14q32.12 Sequence ID: NP_705932.2, NM_153646.3 NP_705933.2, NM_153647.3 NP_705934.1, NM_153648.3 Gene ID: 123041 Splice variants: N/DNCKX4_HUMAN (UniProt)
Gene names: SLC24A4, NCKX4Protein names and data: NCKX4_HUMAN, Full=Sodium/potassium/calcium exchanger 4, Full=Na(+)/K(+)/Ca(2+)-exchange protein 4;Full=Solute carrier family 24 member 4;Flags: Precursor; Length: 622 a.a., Mass: 69042 Da,
fasta formatted sequence
Function: Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+)
Cellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Expressed abundantly in all regions of the brain, aorta, lung and thymus. Expressed at lower levels in the stomach and intestine
Database cross-references
UniProt: Q8NFF2NextBio: 81061
OMIM: 210750 609840
Ensembl: ENST00000532405
GeneCard: GC14P092322
TCDB: 2.A.19.4.5
PharmGenUCSF: SLC24A4
Guide to Pharmacology: SLC24A4 (1048)
SLC24 family of sodium/potassium/calcium exchangers (1048)
HGNC: HGNC:10978