Protein name: SVCT2 Aliases: YSPL2, KIAA0238, NBTL1, NCBT1 Substrates: L-ascorbic acid Transport type: Cotransporter / Na+ Tissue and cellular expression: widespread including brain (neurons), retina, placenta, spleen, prostate, testis, ovary (rat Svct2 also in lung, adrenal, osteoblast) Subcellular expression: N/D Disease: N/D Locus: 20p13 Sequence ID: NP_005107.4, NM_005116.5 NP_976072.1, NM_203327.1 Gene ID: 9962 Splice variants: variant 2 differs in the 5?UTR compared to variant 1 (encodes same isoform)

S23A2_HUMAN (UniProt)

Gene names: SLC23A2, KIAA0238, NBTL1, SLC23A1, SVCT2, YSPL2
Protein names and data: S23A2_HUMAN, Full=Solute carrier family 23 member 2, Full=Na(+)/L-ascorbic acid transporter 2;Full=Nucleobase transporter-like 1 protein;Full=Sodium-dependent vitamin C transporter 2;Short=hSVCT2;Full=Yolk sac permease-like molecule 2; Length: 650 a.a., Mass: 70337 Da,
fasta formatted sequence

Function: Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate
Cellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Ubiquitous

Database cross-references

UniProt: Q9UGH3
NextBio: 37592
OMIM: 603791
Ensembl: ENST00000379333
GeneCard: GC20M004781
TCDB: 2.A.40.6.2
PharmGenUCSF: SLC23A2
Guide to Pharmacology: SLC23A2 (1042)
SLC23 family of ascorbic acid transporters (1042)

HGNC: HGNC:10973

Genetic variants

See also Ensembl:ENST00000379333