Protein name: EAAT5 Aliases: System X-AG Substrates: L-Glu, D/L-Asp Transport type: Cotransporter / Na+, H+, K+ Tissue and cellular expression: retina (rod photoreceptors, bipolar cells) Subcellular expression: N/D Disease: N/D Locus: 1p32.3 Sequence ID: NP_006662.3, NM_006671.4 Gene ID: 6512 Splice variants: N/D

EAA5_HUMAN (UniProt)

Gene names: SLC1A7, EAAT5
Protein names and data: EAA5_HUMAN, Full=Excitatory amino acid transporter 5, Full=Retinal glutamate transporter;Full=Solute carrier family 1 member 7; Length: 560 a.a., Mass: 60658 Da,
fasta formatted sequence

Function: Transports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing
Cellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Expressed primarily in retina. Detectable in liver, heart, muscle and brain

Database cross-references

UniProt: O00341
NextBio: 25323
OMIM: 604471
Ensembl: ENST00000371494
GeneCard: GC01M053087
PharmGenUCSF: SLC1A7
Guide to Pharmacology: SLC1A7 (872)
Glutamate transporter subfamily (872)

HGNC: HGNC:10945

Genetic variants

See also Ensembl:ENST00000371494