SLCtables

SLC18A1

Protein name: VMAT1 Aliases: CGAT, VAT Substrates: 5-HT, DA, NE, epinephrine Transport type: Exchanger / H+ Tissue and cellular expression: sympathetic ganglia, some GI neurons, adrenal medulla Subcellular expression: LDCVs Disease: (unclear) Locus: 8p21.3 Sequence ID: NP_001129163.1, NM_001135691.2 NP_001135796.1, NM_001142324.1 NP_001135797.1, NM_001142325.1 NP_003044.1, NM_003053.3 Gene ID: 6570 Splice variants: N/D

VMAT1_HUMAN (UniProt)

Gene names: SLC18A1, VAT1, VMAT1
Protein names and data: VMAT1_HUMAN, Full=Chromaffin granule amine transporter, Full=Solute carrier family 18 member 1;Full=Vesicular amine transporter 1;Short=VAT1; Length: 525 a.a., Mass: 56257 Da,
fasta formatted sequence
Function: Involved in the vesicular transport of biogenic amines
Cellular location: Cytoplasmic vesicle membrane; Multi-pass membrane protein

Database cross-references

UniProt: P54219
NextBio: 25563
OMIM: 193002
Ensembl: ENST00000440926
GeneCard: GC08M020144
TCDB: 2.A.1.2.12
PharmGenUCSF: SLC18A1
Guide to Pharmacology: SLC18A1 (1011)
SLC18 family of vesicular amine transporters (1011)
HGNC: HGNC:10934

Genetic variants

See also Ensembl:ENST00000440926

4 - 4 T -> P (in dbSNP:rs2270641). VAR_021856 2270641
11 - 11 R -> Q (in dbSNP:rs17092144). VAR_052002 17092144
74 - 74 A -> V (in dbSNP:rs17215815). VAR_024632 17215815
82 - 82 F -> C (in dbSNP:rs17215822). VAR_029149 17215822
84 - 84 F -> S (in dbSNP:rs17215801). VAR_024633 17215801
98 - 98 S -> T (in dbSNP:rs2270637). VAR_020033 2270637
101 - 101 A -> P (in dbSNP:rs17222218). VAR_024634 17222218
136 - 136 I -> T (in dbSNP:rs1390938). VAR_012065 1390938
140 - 140 G -> R (in dbSNP:rs17215808). VAR_029150 17215808
164 - 164 I -> M (in dbSNP:rs17222092). VAR_024635 17222092
202 - 202 I -> T (in dbSNP:rs17222120). VAR_029151 17222120
249 - 249 V -> I (in dbSNP:rs17215759). VAR_024636 17215759
392 - 392 L -> V (in dbSNP:rs17092104). VAR_024637 17092104