Protein name: VGLUT1 Aliases: BNPI Substrates: glutamate Transport type: electrogenic, Cl- dependent Tissue and cellular expression: brain (neurons only), endocrine Subcellular expression: synaptic vesicle Disease: none Locus: 19q13.33 Sequence ID: NP_064705.1, NM_020309.3 Gene ID: 57030 Splice variants: N/D


Gene names: SLC17A7, BNPI, VGLUT1
Protein names and data: VGLU1_HUMAN, Full=Vesicular glutamate transporter 1;Short=VGluT1, Full=Brain-specific Na(+)-dependent inorganic phosphate cotransporter;Full=Solute carrier family 17 member 7; Length: 560 a.a., Mass: 61613 Da,
fasta formatted sequence

Function: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate
Cellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane (By similarity). Membrane; Multi-pass membrane protein (Potential). Cell junction, synapse, synaptosome (By similarity)
Tissue specificity: Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe

Database cross-references

UniProt: Q9P2U7
NextBio: 62781
OMIM: 605208
Ensembl: ENST00000221485
GeneCard: GC19M049429
PharmGenUCSF: SLC17A7
Guide to Pharmacology: SLC17A7 (1007)
Vesicular glutamate transporters (VGLUTs) (1007)

HGNC: HGNC:16704

Genetic variants

See also Ensembl:ENST00000221485