Protein name: MCT6 Aliases: MOT6, MCT5 Substrates: bumetanide, probenecid, nateglinide ? Transport type: N/D Tissue and cellular expression: kidney, muscle, brain, heart, pancreas, prostate, lung, placenta Subcellular expression: N/D Disease: N/D Locus: 17q25.1 Sequence ID: NP_004686.1, NM_004695.2 Gene ID: 9121 Splice variants: several splice variants listed in ENSG00000170190

MOT6_HUMAN (UniProt)

Gene names: SLC16A5, MCT5, MCT6
Protein names and data: MOT6_HUMAN, Full=Monocarboxylate transporter 6;Short=MCT 6, Full=Monocarboxylate transporter 5;Short=MCT 5;Full=Solute carrier family 16 member 5; Length: 505 a.a., Mass: 54994 Da,
fasta formatted sequence

Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity)
Cellular location: Cell membrane; Multi-pass membrane protein
Tissue specificity: Highly expressed in kidney

Database cross-references

UniProt: O15375
NextBio: 34183
OMIM: 603879
Ensembl: ENST00000580123
GeneCard: GC17P075094
PharmGenUCSF: SLC16A5
Guide to Pharmacology: SLC16A5 (995)
SLC16 family of monocarboxylate transporters (995)

HGNC: HGNC:10926

Genetic variants

See also Ensembl:ENST00000580123