SLC16A4

Protein name: MCT5 Aliases: MOT5, MCT4 Substrates: N/D Transport type: Orphan transporter Tissue and cellular expression: brain, muscle, liver, kidney, lung, ovary, placenta, heart Subcellular expression: N/D Disease: N/D Locus: 1p13.3 Sequence ID: NP_001188475.1, NM_001201546.1 NP_001188476.1, NM_001201547.1 NP_001188477.1, NM_001201548.1 NP_001188478.1, NM_001201549.1 NP_004687.1, NM_004696.2 Gene ID: 9122 Splice variants: multiple splice variants listed in ENSG00000168679

MOT5_HUMAN (UniProt)

Gene names: SLC16A4, MCT4, MCT5
Protein names and data: MOT5_HUMAN, Full=Monocarboxylate transporter 5;Short=MCT 5, Full=Monocarboxylate transporter 4;Short=MCT 4;Full=Solute carrier family 16 member 4; Length: 487 a.a., Mass: 54022 Da,
fasta formatted sequence

Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity)
Cellular location: Cell membrane; Multi-pass membrane protein

Database cross-references

UniProt: O15374
NextBio: 34189
OMIM: 603878
Ensembl: ENST00000369779
GeneCard: GC01M110362
TCDB: 2.A.1.13.7
PharmGenUCSF: SLC16A4
Guide to Pharmacology: SLC16A4 (994)
SLC16 family of monocarboxylate transporters (994)

HGNC: HGNC:10925

Genetic variants

See also Ensembl:ENST00000369779