Protein name: PEPT2 Aliases: oligopeptide transporter 2, H+-peptide transporter 2 Substrates: di- and tri-peptides, protons, beta-lactam antibiotics Transport type: Cotransporter / H+ Tissue and cellular expression: apical surface of epithelial cells from kidney and choroid plexus; neurons, astrocytes (neonates), lung, mammary gland, spleen, enteric nervous system Subcellular expression: N/D Disease: lead exposure (*2 haplotype associated with higher blood lead burden in male children) Locus: 3q21.1 Sequence ID: NP_001139470.1, NM_001145998.1 NP_066568.3, NM_021082.3 Gene ID: 6565 Splice variants: N/D

S15A2_HUMAN (UniProt)

Gene names: SLC15A2, PEPT2
Protein names and data: S15A2_HUMAN, Full=Solute carrier family 15 member 2, Full=Kidney H(+)/peptide cotransporter;Full=Oligopeptide transporter, kidney isoform;Full=Peptide transporter 2; Length: 729 a.a., Mass: 81783 Da,
fasta formatted sequence

Function: Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides
Cellular location: Membrane; Multi-pass membrane protein

Database cross-references

UniProt: Q16348
NextBio: 25543
OMIM: 602339
Ensembl: ENST00000489711
GeneCard: GC03P121894
PharmGenUCSF: SLC15A2
Guide to Pharmacology: SLC15A2 (985)
SLC15 family of peptide transporters (985)

HGNC: HGNC:10921

Genetic variants

See also Ensembl:ENST00000489711