Protein name: NKCC1 Aliases: N/D Substrates: Na+, K+, Cl- Transport type: N/D Tissue and cellular expression: ubiquitous Subcellular expression: N/D Disease: N/D Locus: 5q23.3 Sequence ID: NP_001037.1, NM_001046.2 Gene ID: 6558 Splice variants: N/D

S12A2_HUMAN (UniProt)

Gene names: SLC12A2, NKCC1
Protein names and data: S12A2_HUMAN, Full=Solute carrier family 12 member 2, Full=Basolateral Na-K-Cl symporter;Full=Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1; Length: 1212 a.a., Mass: 131447 Da,
fasta formatted sequence

Function: Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume
Cellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Expressed in many tissues

Database cross-references

UniProt: P55011
NextBio: 25519
OMIM: 600840
Ensembl: ENST00000343225
GeneCard: GC05P128083
TCDB: 2.A.30.3.1
PharmGenUCSF: SLC12A2
Guide to Pharmacology: SLC12A2 (969)
SLC12 family of cation-coupled chloride transporters (969)

HGNC: HGNC:10911

Genetic variants

See also Ensembl:ENST00000343225