SLC10A6
Protein name: SOAT Aliases: P6 Substrates: estrone-3-sulfate, dehydroepiandrosterone sulfate, pregnenolone sulfate Transport type: Cotransporter / Na+ Tissue and cellular expression: testis, placenta, pancreas Subcellular expression: N/D Disease: N/D Locus: 4q21.3 Sequence ID: NP_932069.1, NM_197965.2 Gene ID: 345274 Splice variants: N/DSOAT_HUMAN (UniProt)
Gene names: SLC10A6, SOATProtein names and data: SOAT_HUMAN, Full=Solute carrier family 10 member 6, Full=Sodium-dependent organic anion transporter; Length: 377 a.a., Mass: 41259 Da,
fasta formatted sequence
Function: Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner
Cellular location: Membrane; Multi-pass membrane protein (Potential)
Tissue specificity: Highly expressed in testis, placenta and pancreas. Moderately expressed in heart, lung and mammary gland. Weakly expressed in brain, colon, kidney, liver, ovary, prostate, small intestine, spleen and thymus
Database cross-references
UniProt: Q3KNW5NextBio: 98841
OMIM: 613366
Ensembl: ENST00000273905
GeneCard: GC04M086823
TCDB: 2.A.28.1.4
PharmGenUCSF: SLC10A6
Guide to Pharmacology: SLC10A6 (961)
SLC10 family of sodium-bile acid co-transporters (961)
HGNC: HGNC:30603